Our group previously reported [99mTc]Tc-((R)-1-((6-hydrazinylnicotinoyl)-D-alanyl)pyrrolidin-2-yl) boronic acid ([99mTc]Tc-iFAP) as a new SPECT radioligand capable of specifically detecting FAP expressed by CAFs located in the cancer stroma and, to our knowledge, the first ligand based on 99mTc-labeled boron-Pro derivatives [8]. This evidence concerns the gene FAP and cancer.