ACHE and Alzheimer disease: In our previous works, we synthetized and studied new molecules, characterized by two small aromatic moieties separated by various functionalized linkers, designed as new dual binding AChE and BChE inhibitors, able to bind both CAS and PAS of the enzymes, as well as being endowed with other properties, such as anti-aggregating activity, chelating and antioxidant abilities, which are potentially interesting in the light of the multifunctional nature of AD [30,31,32].