NPPB and Schnyder corneal dystrophy: In patients with ischemic HF eligible for implantable cardioverter defibrillator (ICD) for primary prevention of SCD the extent of 11C-HED assesses impaired cardiac sympathetic innervation was a predictor of SCD independently of LVEF, infarct volume, cardiac symptoms, and brain natriuretic peptide (BNP) plasma levels [65].