CDH5 and dengue disease: The altered expression and/or distribution of IJC proteins such as VE-cadherin, ZO-1, and β-catenin has been described in in vitro assays with epithelial and endothelial cells after DENV or other flaviviral infections [59,60,61,62,63,64,65,67,68,69,70,71], stimulation of human ECs with soluble factors circulating in sera from dengue patients [72,73,74] or secreted from DENV-infected cells [18,75], as well as in DENV and ZIKV NS1-stimulated umbilical vein ECs, ex vivo human chorionic explants, and dermal ECs [10,23,39,40,58,76,77].