However, incubation in MetS BALF, resulted in the accumulation of 15 distinct proteins, including alpha-enolase, coiled-coil domain-containing 146, exocyst complex component 6B, retinal dehydrogenase 1, selenium-binding protein 1, myosin-14, Heat shock protein HSP 90-beta, cytochrome b5, cytochrome P450 2F2, chitinase-3-like protein 1, bicaudal D-related protein 1, proteasome subunit beta type-6, pigment epithelium-derived factor, apolipoprotein C-III, and protease, serine 1 (trypsin 1). The gene discussed is PSMB6; the disease is metabolic syndrome.