SLC30A6 and fragile X-associated tremor/ataxia syndrome: ZnT6 has been linked to various detrimental phenotypes and pathologies in humans, including mild cognitive impairment [281,282], ALS [259], Fragile X-associated tremor/ataxia syndrome (FXTAS) [283,284], early [282,285,286] and late [262,282] models of AD, and pancreatic cancer [287].