The beneficial effect of synbiotics on the metabolic profile of people with hyperglycemia (glycemia, biomarkers of inflammation, and oxidative stress) may result from the stimulation of the microbial production of SCFAs, which in turn leads to an increase in the concentration of glucagon-like peptide-1 (GLP-1) and inhibits hyperglycemia [177,209]. This evidence concerns the gene GCG and Hyperglycemia.