Consequently, since the beginning of the pandemic, the effects that the stimuli of VDR would have on the respiratory distress induced by SARS-CoV-2 have been described [64,65], suggesting a possible link between low levels of 25(OH)D and severity of COVID-19, as supported by the more than 1000 references that appear in PubMed with the keywords “COVID-19” and “vitamin D”. The gene discussed is VDR; the disease is COVID-19.