Moreover, single-nucleotide variants (SNVs) in the APOA5 gene, such as rs651821 and rs3135506, have been associated with metabolic syndrome and its traits, [8,9,10,11,12]; recently, the involvement of rs662799 (−1131T > C) [13] in lipid profile and metabolic syndrome has been shown too. The gene discussed is APOA5; the disease is metabolic syndrome.