Regarding the tumor visualization, the scrambled analogs [68Ga]25a and [68Ga]25b were less efficient compared to the bispecific ligand [68Ga]25, a finding that indicates that both parts of HBPL [68Ga]25 were necessary to enhanced in vivo tumor uptake and that this uptake was GRPR- and NPY Y1-specific. Here, GRPR is linked to neoplasm.