STAT3 and cancer: Overexpressed signal transducer and activator of transcription 3 (STAT3) are highly associated with cancer initiation, metastasis, cell survival, cell cycle progression [66,119], proliferation, migration, invasion, anti-apoptosis, angiogenesis, chemoresistance, immunosuppression, and stem cell self-renewal and differentiation of TNBC cells of clinical and preclinical studies [120,121].