JUN and peritonitis: The ethanolic extract of Myrsine seguinii is rich in Q, which was found to inhibit inflammatory responses (such as production of NO• and PGE2) in LPS-stimulated RAW264.7 cells and LPS-induced mouse peritonitis by blocking the Src/Syk/nuclear factor kappa B (NF-κB) and the IL-1 receptor-associated kinase 1/activator protein 1 (IRAK-1/AP-1) pathways [31].