The treatment was performed in 28 days (T28) followed by a follow-up period of 28 days (T56), evaluating the gut microbial composition and modulation, the variability of fecal parameters including β-defensin2 and calprotectin, and salivary IgA, salivary total antioxidant capacity (TAC), and common infectious disease incidence (CID) as markers of well-being condition of all elderly subjects. The gene discussed is CD79A; the disease is infectious disease.