Neuropeptides receptors such as neurokinin-1 receptor (NK1R) and Receptor activity modifying protein (RAMP) are expressed on T cells and antigen-presenting cells (such as monocytes and endothelial cells), and can influence the functions and immune responses of T helper type 17 (Th17) cells, which are known to play a critical role in the pathogenesis of psoriasis [29]. This evidence concerns the gene TACR1 and psoriasis.