SPP1 and liver dysplastic nodule: Urine biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), beta-2 microglobulin (β2-M), kidney injury molecule-1 (KIM-1), liver-type fatty acid-binding protein (L-FABP), osteopontin (OPN), and N-acetyl-β-D-glucosaminidase (NAG), have been extensively studied to detect DN among the pediatric population [10].