It is estimated that approximately 20% of patients with hypertriglyceridemia carry only six common LPL gene mutations (Asp9Asn, Asn291Ser, Trp86Arg, Gly188Glu, Pro207Leu, Asp250Asn) associated with type I hyperlipoproteinemia. This evidence concerns the gene LPL and familial chylomicronemia syndrome.