In fact, virtually all stages of the disease, including MGUS, SMM, and MM tumors, have dysregulated and/or increased expression of cyclin D1, cyclin D2, or cyclin D3, including translocations involving MAF, MAFB, fibroblast growth factor 3 (FGFR3), and HRD disease [3,4]. The gene discussed is CCND1; the disease is Miyoshi myopathy.