In our results, some COVID-19 mutations associated with mild disease were also found, such as nsp14:I164ILV, ORF8:L84S, nsp4:F308Y, nsp6:L37F, ORF3a:G196V, N:P13L, nsp4:M324I, and N:G204R. This evidence concerns the gene PRSS57 and COVID-19.