BCL2 and neoplasm: Related studies have shown that long-chain fatty acids may induce apoptosis by enhancing lipid peroxidation, mainly by inhibiting the expression of B lymphoma-2 gene (Bcl-2) via phosphorylation and enhancing the activity of cytochrome P450; these long-chain fatty acids may have cytotoxic effects on tumor cells at the level of oncogene expression [155].