Studies have shown that the inhibition of FAS in breast cancer cells can lead to the accumulation of propane two coenzyme A, resulting in the up-regulation of carnitinepalmityltransferase-1 (CPT-1) and ceramide and the induction of apoptosis, and the production of apoptotic genes BNIP3, TRAIL, and DAPK2, resulting in the apoptosis of tumor cells [167]. The gene discussed is FAS; the disease is neoplasm.