VAV1 and acute myeloid leukemia: To explore the involvement of other miRNA/s with a known role in targeting Akt2, we focused on miR-29b, whose gene transcription is positively regulated by Vav1 in acute myeloid leukemia [18] and in MDA-MB-231 cells [24] and that is known to target Akt2 in glioblastoma, gastric and ovarian cancers [21,34].