ACE2 and infection: Furthermore, considering that the expression of ACE2 could be noted, not only in the lungs, but also in the renal and cardiac systems, it could represent a plausible explanation for the correlation between the infection with SARS-CoV-2 and these two systems, including the presence of various manifestations, such as arrhythmias [16], acute cardiac, and renal injury [14,15], potentially inducing the onset of a secondary cardiorenal syndrome.