The expression of proinflammatory cytokines has been reported in several CFTR-deficient human CRC cell lines, including CaCO−2 and HT-29 cells [114,117,118,119], and outside the GI tract CFTR has been shown to regulate the proliferation, migration and invasion of cervical cancer cells via inhibition of NF-κB signaling [120]. This evidence concerns the gene NFKB1 and colorectal carcinoma.