IKZF1 and acute lymphoblastic leukemia: In recent years, Genome-Wide Association Studies (GWASs) have identified a number of loci associated with the risk of developing ALL, including the ARID5B, IKZF1, PIP4K2A, CEBPE, GATA3, BMI, and CDKN2A genes [6,7,8,9,10,11].