Indeed, the liver health and coagulation axis appears as a relevant surrogate for elucidating some COVID-19 outcomes linked to systemic inflammation [43], as well as thrombotic and fibrinolytic disturbances [44], which were deciphered in the currently emerged three clusters, including some markers of global health such as lactate dehydrogenase or creatinine/urea measurements [45], as particularly discriminated in Cluster C. Interestingly, hemoglobin and prothrombin values evidenced divergent patterns after the following 72-h period, which represent a worth for a cluster monitor. Here, F2 is linked to COVID-19.