This effect was demonstrated in a translational study that illustrates the IgG-mediated regulation of thymic γδT cells IL-17 production, with some possible implications for allergy development [32], and also in a human approach where IgG from nonatopic individuals can modulate the production of IFN-γ and IL-10 on thymic and peripheral γδT cells [33]. Here, IL10 is linked to Allergy.