Corticotrope adenomas are rare in MEN1, representing 4.4–5% of all pituitary histotypes [78,79,80]; when considering proband patients presenting with a pituitary adenoma as the first sign of MEN1, this percentage arises to 15.4% [79], highlighting that corticotrope adenomas may be the first manifestation of this syndrome. The gene discussed is MEN1; the disease is pituitary gland adenoma.