CDKN1A and pituitary gland adenoma: In fact, a subsequent study searched and found CDK-inhibitors potential (but not certainly) pathogenic mutations in seven of 196 patients affected by MEN1-like syndrome: one of them carried a CDKN1B mutation and had no pituitary adenomas, while a patient and one of her relatives carrying a CDKN1A/p21 mutation were affected by a prolactinoma; none of these seven patients were affected by Cushing’s disease [92,93].