LRRK2-mutated PD patients also show the classical dopaminergic neuron lost characteristic of PD [168] but, surprisingly, there is no evidence of α-syn aggregation in Lewy’s Bodies in some LRRK2-mutated PD cases [169,170,171,172], with α-syn levels even lower compared to idiopathic PD patients [173]. Here, LRRK2 is linked to Parkinson disease.