Similarly, a canine model has been identified with a spontaneous CNGB1 mutation, c.2387delA;2389_2390insAGCTAC in exon 26, leading to a frameshift and premature stop codon, which closely resembles the Cngb1-X26 mouse and human RP phenotype [20]. This evidence concerns the gene CNGB1 and retinitis pigmentosa 1.