Moreover, mitochondria-targeted antioxidant SkQ1 has been shown to ameliorate clinical signs of retinopathy in OXYS rats (manifesting signs of age-related macular-degeneration-like retinopathy) by influencing the transcriptional activity of AhR and Nrf2 and mRNA expression levels of CYP1A2 and CYP1B1 in the retina of OXYS and Wistar rats. Here, AHR is linked to retinal disorder.