NFE2L2 and retinal disorder: Moreover, mitochondria-targeted antioxidant SkQ1 has been shown to ameliorate clinical signs of retinopathy in OXYS rats (manifesting signs of age-related macular-degeneration-like retinopathy) by influencing the transcriptional activity of AhR and Nrf2 and mRNA expression levels of CYP1A2 and CYP1B1 in the retina of OXYS and Wistar rats.