EPAS1 and pancreatic neoplasm: We used the Gene Expression Profiling Interactive analysis (GEPIA) database (http://gepia.cancer-pku.cn/ accessed on 16 April 2021) to analyze the HIF-2α mRNA level in pancreatic cancer tissues and normal pancreatic tissues and found that HIF-2α mRNA levels were significantly higher in pancreatic cancer tissues than in normal pancreatic tissues (p < 0.05; Figure 1d).