In our clinical study, the number of HDM antigens observed in the epidermis was low in the non-spongiotic area of lichenified eczema, and most of these antigens were captured by IgE+ LCs (approximately five on average per 0.24 mm2 in a 200× visual field) (Figure 3d). The gene discussed is IGHE; the disease is Eczematoid dermatitis.