Therefore, TRPM8 could be considered a useful target to block PCa growth by using TRPM8 antagonists, such as capsazepine [16], BCTC [20], cannabigerol [42], as well as TRPM8 agonists, including menthol [15,16] and D–3263 [43], depending on the cancer stage. The gene discussed is TRPM8; the disease is cancer.