It has been reported that many signaling pathways are involved in autophagy, such as the AMPK/mTOR pathway [68] and the Hippo/Yes-associated protein (YAP) pathway [69]; therefore, in addition to the mTOR/RPS6KB1 pathway, whether EVA1A can regulate autophagy through other methods in GBM needs to be further studied. Here, RPS6KB1 is linked to glioblastoma.