CXCL1P1 and colorectal carcinoma: The stage IV CRC showed a significantly higher rate of positive GroP expression than the other stages (stage 0, 14% (2/12); stage I, 25% (5/20); stage II, 43% (9/21); stage III, 36% (8/22); stage IV, 74% (17/23)) (Figure 1B).