SIAH1 and Infertility: This search revealed that in the case of NANOS1 overexpression, three infertility related genes (CREBBP, CCNB1, and NPAS2) and five cancer-germ cell genes (CENPL, ERCC6L, KIF18A, SIAH1, and TRIM71) were present in three clusters (Figure 2B and Figure S3).