The study with 91 patients with HT (42 with hypothyroidism and 49 euthyroidism) and 50 healthy people found that the levels of inflammatory factors, including interleukin 6 (IL-6), 12, 10 and tumor necrosis factor-α (TNF-α) were lower in the control group compared to the HT group. This evidence concerns the gene TNF and hypothyroidism.