WNT5A and infection: Upon infection by mycobacteria, WNT5A was induced in antigen-presenting T cells in a TLR-NF-κB-dependent manner, where it mediates the secretion of IL-12 and IFN [103], and both WNT5A and WNT3A were found to inhibit TLR-induced secretion of proinflammatory cytokines in DC [98,104].