The genes known to be recurrently mutated in NB are: ALK, TERT, ATRX, LIN28B, TP53, SMARCA4, CDKN1B, PHOX2B, CHD5, MYCN, SHANK2, PTPRD, FGFR1, PTPN11, NF1, NRAS, KRAS, and BRAF [6]. This evidence concerns the gene PTPN11 and neuroblastoma.