Hectors et al. [54] was the only included study focusing on hepatocellular carcinoma (HCC), and it showed a correlation between MRI radiomic features and PD1 and CTLA4 at mRNA expression level, and the significant predictive ability of the radiomic features regarding early HCC recurrence, but it did have some limitations and a moderate risk of bias. This evidence concerns the gene CTLA4 and hepatocellular carcinoma.