Notably, GPR18 expression is also associated with better prognosis in cervical cancer (CESC), another HPV+ tumor, as well as in different malignancies such as urothelial bladder carcinoma (BLCA), mesothelioma (MESO) and skin cutaneous melanoma (SKCM), further corroborating its tumor-protective role [25]. The gene discussed is GPR18; the disease is cutaneous melanoma.