Recently, Li and his colleagues suggested that ginsenoside 20(S)-Rg3 inhibits the Warburg effect via inhibition of STAT3 signaling [14], and Lin et al. reported that matrine significantly inhibited proliferation and induced apoptosis by regulating the Warburg effect through controlling hexokinases 2 (HK2) expression in myeloid leukemia cells. This evidence concerns the gene HK2 and myeloid leukemia.