DNER and posterior cortical atrophy: Interestingly, D0 in PCa cells treated with a combination of BET and RT decreased from 3.2 Gy to 2.6 Gy in PC3 cells, from 3.2 Gy to 2.9 Gy in DU145 cells, and from 1.8 Gy to 1.65 Gy in LN-C42B cells, compared to RT alone, suggesting an additional killing effect.