The Gal4-dependent upregulation of PURB (transcriptional activator protein Pur-beta) and MAPKAPK3 (MAPK-Activated Protein Kinase 3) expression, as well as the downregulation of BTF3 (Basic Transcription Factor 3) and BCAR1(Breast Cancer Anti-Estrogen Resistance Protein 1), could be confirmed (Figure 5). This evidence concerns the gene PURB and medical procedure.