FGF23 and chronic kidney disease: The pathophysiological interplay of CKD and mineral bone disorder [5] includes abnormalities of calcium, phosphorus, parathyroid hormone, fibroblast growth factor 23, and vitamin D. It results in osteodystrophy, an increased fracture risk and extra-osseous calcifications, including vascular calcifications and thus contributes to the exceedingly high cardiovascular morbidity and mortality in patients with CKD [6,7].