CDC73 and parathyroid gland carcinoma: In previous studies, expression of transcripts of a splice mutation in the CDC73 gene in HPT-JT syndrome was detected by real-time PCR in parathyroid carcinoma tissue, whereas the corresponding CDC73 protein was not detected [18,19], and it was shown that the mutant CDC73 mRNA transcribed from the splice mutation was stable in tissue cells, whereas the protein product was rapidly degraded [19].