This could lead us to think of alterations in the regulation of inflammation mediated by Il-22 induced by dysbiotic changes that occur in peri-implantitis, which could be related to differences observed in the progression of periodontal and peri-implant diseases, where a faster progression pattern has been described for the infection around implants when compared to the infection around teeth [30]. Here, IL22 is linked to Peri-Implantitis.