TCF7L2 and colorectal carcinoma: For example, by interacting with heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) to upregulate the expression of transcription factor 7 like 2 (TCF7L2) that activates Wnt signaling, lncRNA MIR100HG acts as an inducer of epithelial–mesenchymal transition (EMT), which facilitates cetuximab resistance and metastasis in CRC [26].