Of these, PRLR has been implicated in the pathology of breast and prostate cancer [46,47], NOX1 expression may be increased in prostate cancer with an important role in angiogenesis, cell growth, and tumor pathogenesis [48,49], and both AMH and PGF are reported as crucial genes in tumorigenesis [50,51,52]. Here, NOX1 is linked to Familial prostate cancer.