Moreover, to confirm the link between the number of peritumoral neutrophils and the greater biological aggressiveness of gliomas, patients with IDH-1 wild-type glioma, which is mostly associated with a poorer prognosis, have higher peritumoral neutrophil levels than low-grade, IDH1-mutated gliomas [32,34,35]. The gene discussed is IDH1; the disease is glioma.