DGUOK-AS1 targets miR-1-3p (which facilitates Th17 differentiation [45]), miR-138-5p (which promotes TNFα-induced apoptosis through PTEN/PI3K/Akt signaling [46]), miR-148a-3p and miR-148b-3p (the primary biomarker for lupus nephritis [47] and a potent PTEN activator), miR-151a-3p (another biomarker of lupus nephritis [48]), miR-653-5p (an miRNA active in Behçet’s syndrome inflammation [49]), and miR-876-3p (which modulates proliferation and apoptosis in lymphocytic leukemia through JNK signaling [50]). Here, PTEN is linked to lupus nephritis.